Newcastle United dared to dream against last season's treble champions Manchester City - and sent Pep Guardiola's side away with nothing but their bus fare home.

Pep had moaned about the lack of a flight back to the North-West but his players were left to contemplate what might have been after Newcastle inflicted a big scalp on the side from the Etihad Stadium. Alexander Isak's second half goal was enough to secure a place in the last 16 for the Magpies, who can now dream about a trip to the famous Wembley arch once again.

Guardiola continued his sulk throughout the night and even ended up on a yellow card but the trophy serial winner knew his team had been beaten by the better side. And so Newcastle march on.

Howe named a much-changed line-up with 10 players handed an opportunity to impress and just one survivor in Joelinton from the XI that began the Carabao Cup final against Manchester United last winter. It could have been deemed a gamble by Howe, but by the end it looked like a great managerial move as his team got the job done, even if it was with a little help by some of his A-listers.

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It was a tame opening to the game on a mild but wet night on Tyneside with neither Stefan Ortega or Nick Pope having a save to make in the first 10 minutes. The first chance of the night finally arrived on 18 minutes when Oscar Bobb slipped in Julian Alvarez but Pope saved with his foot before United cleared their lines.

City threatened again mid-way through the first half as Jack Grealish probed in the final third but Paul Dummett snapped into a fine challenge to the delight of the Gallowgate End. The visitors had 71% possession in the opening half an hour and Alvarez swiped wildly at goal just before that 30-minute milestone but it swerved wide of Pope's goal.

Some jitters from Lewis Hall on 32 minutes saw him hit a heavy backpass to Pope with the ball bouncing out for a corner kick. Howe tweaked his line up with Hall and Matt Targett swapping slots as they tried to find a breakthrough.

The two sides went in level at the break with City the better of the two sides despite failing to find a goal. Howe must have sensed something similar as he made two changes at half-time.

Howe took off teenagers Lewis Miley and Hall at the break and introduced more experience with Bruno Guimaraes and Anthony Gordon. The freshen up at the interval didn't take long to pay off.

Gordon steamed into a challenge on Matteo Kovacic and seemed to re-ignite a crowd that had been taunted by City's own fans for being as quiet as the Etihad Stadium! The roof was then raised eight minutes into the second half a run down the middle from Murphy saw him pick out Joelinton.

Joelinton arrowed his way into the box and swept it to the back post with Alexander Isak - a frustrated observer during the first half - applying the finish to beat Ortega. Three minutes later Isak broke into the box and fired another shot at Ortega.

Newcastle looked like a different team to the one that had paid City a lot of respect in the first half. The Magpies made it past the hour mark with their lead intact before Howe made another change.

Having played his part Isak was withdrawn and replaced by Miguel Almiron for the closing stages as United tried to see the game out. Man City flexed their financial muscle when introducing Matheus Nunes and Jeremy Doku for the last quarter of the game.

England star Phil Foden was also thrown into the battle with 18 minutes to go at St James' as the man dubbed the "Stockport Iniesta" replaced Alvarez was tasked with saving the night. Grealish had a run at the Newcastle defence before firing it at Pope but the Toon stopper easily gathered.

Livramento summed up his excellent full debut performance with a crisp and near-perfectly timed challenge on Nunes in front of the Leazes End with seven minutes to go. City threatened when Rico Lewis fired wide in the 90th minute but Pope had it covered.

Tonali went off to a standing ovation with Elliot Anderson handed a cameo role for the dying stages. The fourth official Sam Allison displayed six minutes of added time with Newcastle closing in on a big result.

Having watched Gordon test the keeper late on, Joelinton curled a shot low down but again Ortega saved. Dummett's last gasp clearance resulted in an injury for the long serving star with Fabian Schar thrown into the stoppage-time battle.

But Newcastle defended their lines superbly in the closing stages to leave City floored and Toon fans wondering what might be later in the season.

Referee: Chris Kavanagh

Attendance: 51,692